She often focuses on the situation of groups or individuals that are from various reasons excluded, discriminated, silenced. She tries to find alternative ways of expression for those who are not able to communicate and integrate in the standard way. Koťátková creates installations made up of objects, drawings, collages, photographs, video, performance and text which engage the spectator in new environments to expose them to new perceptual experiences and approaches.
She is a co-founder of a platform Institute of Anxiety that sees anxiety as a result of social, political, economic and ecological forces. It argues that there is a potential for positive change both in attempting structural changes and system critique but also in diverse acts of sharing.

A Storyteller's Inadequacy. Speech organ of Anna, a girl who pronounces words from the middle, 2013 Installation view, Modern Art Oxford, 2013
Courtesy the artist and hunt kastner, Prague
Photo: Stuart Whipps for MAO, Oxford

Not How People Move But What Moves Them, 2014-5
Installation view, New Museum Triennial, New York, 2015
Courtesy the artist and hunt kastner, Prague
Photo: Benoit Pailley for the New Museum, New York

The Dream Machine is Asleep, 2018
Exhibition view at Pirelli HangarBicocca, Milan, 2018
Courtesy of the artist and hunt kastner, Prague
Photo: Agostino Osio for Pirelli HangarBicocca, Milan

Confessions of a Piping System, 2019
Installation view, Kunsthal Charlottenborg, 2019
Courtesy the artist and hunt kastner, Prague
Photo: David Stjernholm for Kunsthal Charlottenborg, Stockholm

Machine for Restoring Empathy, 2019
Installation view, 16th Istanbul Biennale
Courtesy of the artist and hunt kastner, Prague
Photo: Sahir Ugur Eren for the Istranbul Biennale

Interview with a Monster, 2021
View from the exhibition, Meet Factory Prague
Courtesy of the artist and hunt kastner, Prague
Photo: Studio Flusser for Meetfactory, Prague

My Body is not an Island, 2021-2
Courtesy of the artist and hunt kastner, Prague
Photo: Aleksandra Vajd, Prague

My Body is not an Island, 2021-2
Courtesy of the artist and hunt kastner, Prague
Photo: Aleksandra Vajd, Prague